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Best NVIDIA GPUs for HPE ProLiant Servers

  • Writer: server-parts.eu server-parts.eu
    server-parts.eu server-parts.eu
  • Mar 29
  • 4 min read

Updated: Apr 5

HPE ProLiant servers are widely used in enterprise environments, and many organizations are looking to add compatible NVIDIA GPUs to improve performance. Whether you're considering purchasing a complete HPE ProLiant server with NVIDIA GPUs or upgrading your existing setup, knowing which GPUs are compatible can be challenging.


NVIDIA GPUs and GPU Servers: Save Up to 80%

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In this article, we'll guide you through the best NVIDIA GPU options for your HPE ProLiant servers.


Detailed compatibility guide for NVIDIA GPUs in HPE ProLiant DL360, DL380, DL560, and DL580 servers across Gen10, Gen10+, and Gen11 models. Features NVIDIA A100, H100, A40, A30, RTX A5000, RTX 6000 Ada, L40, and A16 GPUs for AI training, deep learning, HPC workloads, virtualization (VDI), and graphics rendering. Includes PCIe Gen4 and Gen5 support, power requirements, and optimal GPU configurations for enterprise data centers. Server-parts.eu

 

HPE ProLiant DL360 GPU Server Series


HPE ProLiant DL360 Gen10 GPU Servers


Key Features:

  • ✅ Supports 1 low-profile GPU

  • ✅ Best for VDI environments and lightweight inference workloads


Supported GPUs:

  • NVIDIA A16 64GB – Ideal for VDI, supporting up to 64 virtual desktops per card

  • NVIDIA T4 16GB – For VDI and low-power AI inference

  • NVIDIA P4 – Great for ultra-low power inference (legacy but still used)


Important Considerations:

  • Requires a GPU enablement kit for installation

  • High-performance fans are necessary to manage cooling for this 1U server


 

HPE ProLiant DL360 Gen10+ GPU Servers


Key Features:

  • ✅ Supports 2 low-profile GPUs

  • ✅ Enhanced PCIe Gen4 support for improved bandwidth

  • ✅ Great for VDI, inference workloads, and light AI tasks


Supported GPUs:

  • NVIDIA A2 16GB – Ideal for efficient AI inference and video processing

  • NVIDIA A10 24GB – Excellent for virtual workstations and moderate AI workloads

  • NVIDIA A16 64GB – Optimized for high-density VDI environments

  • NVIDIA T4 16GB – A solid Gen4-compatible low-power GPU for inference


Important Considerations:

  • GPUs exceeding 75W require:

    • Power cable kit

    • Upgraded fans for better cooling


 

HPE ProLiant DL360 Gen11 GPU Servers


Key Features:

  • ✅ Supports 2 low-profile GPUs

  • ✅ Improved PCIe Gen5 support for higher bandwidth

  • ✅ Ideal for inference workloads, VDI, and light creative work


Supported GPUs:

  • NVIDIA L4 24GB – Optimized for AI inference and video analytics

  • NVIDIA RTX 4000 Ada – Excellent for creative workstations and graphics workloads

  • NVIDIA A16 64GB – Designed for dense VDI deployments

  • NVIDIA A30 24GB – Low-profile compatible and great for AI inference


Important Considerations:

  • Enhanced cooling and power cables are essential for GPUs exceeding 75W


 

HPE ProLiant DL380 GPU Server Series


HPE ProLiant DL380 Gen10 GPU Servers


Key Features:

  • ✅ Supports up to 2 full-height, full-length GPUs

  • ✅ Perfect for AI inference, data visualization, and VDI


Supported GPUs:

  • NVIDIA A10 24GB – Suitable for virtualization and moderate AI workloads

  • NVIDIA A30 24GB – Great for AI inference and distributed training

  • NVIDIA A40 48GB – Ideal for graphics rendering and visualization tasks

  • NVIDIA A16 64GB – High-density VDI accelerator

  • NVIDIA T4 16GB – For lightweight tasks

  • NVIDIA V100 32GB – For HPC and AI acceleration on Gen3


Limitations:

  • The NVIDIA A100 80GB is not supported due to PCIe Gen3 limitations


Important Considerations:

  • GPUs exceeding 150W require:

    • Power cables

    • A GPU enablement kit


 

HPE ProLiant DL380 Gen10+ GPU Servers


Key Features:

  • ✅ Supports up to 3 full-height, full-length GPUs

  • ✅ Great for AI training, graphics, and VDI


Supported GPUs:

  • NVIDIA A2 16GB – Energy-efficient AI inference

  • NVIDIA A10 24GB – Versatile for virtual workstations and rendering

  • NVIDIA A30 24GB – Strong AI inference and scalable workloads

  • NVIDIA A40 48GB – Powerful for large data visualization

  • NVIDIA A100 80GB – Exceptional for AI training and HPC workloads


Important Considerations:

  • GPUs exceeding 300W require:

    • A GPU enablement kit

    • Enhanced cooling solutions


 

HPE ProLiant DL380 Gen11 GPU Servers


Key Features:

  • ✅ Supports up to 4 full-height, full-length GPUs

  • ✅ Optimized for AI, HPC, and data-heavy workloads


Supported GPUs:

  • NVIDIA A10 24GB

  • NVIDIA A16 64GB

  • NVIDIA A30 24GB

  • NVIDIA A40 48GB

  • NVIDIA H100 80GB – Advanced AI model training and large data workloads

  • NVIDIA L40 48GB – Optimized for powerful rendering and visual computing

  • NVIDIA RTX 6000 Ada – Ideal for professional visualization and creative workloads


Important Considerations:

  • Multi-GPU configurations require:

    • Upgraded power supplies

    • Enhanced cooling solutions


 

HPE ProLiant DL560 GPU Server Series


HPE ProLiant DL560 Gen10 GPU Servers


  • Key Features:

    ✅ Supports up to 2 GPUs (Gen3 PCIe)

    ✅ Suitable for HPC, inference, and legacy AI workloads


  • Supported GPUs:

    • NVIDIA T4 16GB – Energy-efficient GPU for inference and VDI

    • NVIDIA V100 32GB – High-performance GPU for HPC and AI workloads


  • Important Considerations:

    • Requires a GPU enablement kit for installation

    • Enhanced cooling and power cabling may be necessary for GPUs over 150W

    • Compatibility may vary depending on BIOS and system configuration


 

HPE ProLiant DL560 Gen11 GPU Servers


Key Features:

  • ✅ Supports up to 2 GPUs

  • ✅ Designed for AI, HPC, and scientific computing


Supported GPUs:

  • NVIDIA H100 80GB – Cutting-edge AI performance with advanced data handling

  • NVIDIA A40 48GB – Powerful for visual computing and simulation

  • NVIDIA L40 48GB – Strong for rendering and AI


Important Considerations:

  • Requires a GPU enablement kit and enhanced power delivery for stability under heavy workloads


 

HPE ProLiant DL580 GPU Server Series


HPE ProLiant DL580 Gen10 GPU Servers


Key Features:

  • ✅ Supports multiple high-performance GPUs

  • ✅ Suitable for AI training, HPC, and large-scale visualization


Supported GPUs:

  • NVIDIA A40 48GB – Designed for rendering and visual computing

  • NVIDIA A100 80GB – Exceptional for demanding AI and HPC workloads

  • NVIDIA V100 32GB – Popular for HPC in Gen3-based platforms


Important Considerations:

  • Dual 1600W power supplies recommended for stability under load


 

HPE ProLiant DL580 Gen11 GPU Servers


Key Features:

  • ✅ Supports multiple high-performance GPUs

  • ✅ Designed for graphics, AI, and data-heavy workflows


Supported GPUs:

  • NVIDIA L40 48GB – Ideal for high-end rendering and graphics

  • NVIDIA A40 48GB – Powerful visualization GPU

  • NVIDIA H100 80GB – For AI performance at the highest level

  • NVIDIA RTX 6000 Ada – Excellent for high-end creative and AI-driven graphics workloads


Important Considerations:

  • Multi-GPU configurations require:

    • Upgraded cooling

    • High-wattage power supplies to maintain performance


 

NVIDIA GPUs and GPU Servers: Save Up to 80%

✔️ No Upfront Payment Required - Test First, Pay Later!

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